Sengge Rinchen came from the Horqin Left Black Banner in Inner Mongolia and belonged to the Borjigin clan, which could trace its origins back to Genghis Khan. His personal name consists of the words for "lion" and "treasure" respectively. In 1825, he became an imperial prince of the second degree .
Sengge Rinchen is mainly known for his role in a number of military campaigns in the mid-nineteenth century. In 1853, Sengge Rinchen stopped the northern expedition of Taiping army and captured one of its leaders, Li Kaifang. In 1855, Sengge Rinchen's status was elevated to Prince of the First Degree in recognition of this.
Four years later during the Second Opium War, he was appointed imperial commissioner in charge of leading the campaign against the and invasion. In 1859, he was defeated by the British and French forces at the Taku Forts and he was subsequently transferred to fight against the Nian rebellions, which he fought successfully and earned him back all his former titles and ranks. In 1865, during a campaign against the Nian Shandong, Sengge Richen was ambushed by a group of Nian rebels and killed. The was finally suppressed in 1868.
Following his death, the imperial court canonized Sengge Rinchen in recognition of his service to the Qing dynasty and made his rank as imperial prince hereditary under the name of the "loyal prince" . In 1889, Empress Dowager Cixi ordered that a shrine be erected in his memory under the name ''Xianzhongci'' , which still stands in the in Beijing.
In official history works in the People's Republic of China's, Sengge Rinchen's Qing loyalist stance is interpreted as an expression of his Chinese patriotism, and in 1995, the local government of Tongliao in Inner Mongolia opened a Sengge Rinchen memorial museum. In , however, historians tend to give a less approving view of Sengge Rinchen, given his close association with China.